NeuroRehab Team
Thursday, October 23rd, 2025
Stroke patients experience rapid muscle loss, with motor units declining in just 4 hours after onset and muscle atrophy developing by day 10. A TENS unit gives stroke patients a medication-free way to handle pain. NMES works as an external stimulator that reinforces neural pathways and activates muscles.
Patients need to know the key differences between these electrical stimulation options. NMES helps build muscle strength and coordination, while TENS therapy targets pain management. Research shows that combining both therapies with targeted exercises boosts neuroplasticity more than using either method by itself. Post-stroke spasticity affects 4% to 27% of patients by week six and rises to 42.6% by month six. This makes early intervention a vital part of recovery.
This piece breaks down NMES and TENS differences in stroke recovery. You’ll find details about electrode placement, safety guidelines, and how to pick the right device. Physical therapy blends well with functional electrical stimulation to maximize recovery results. The information here will help you choose the best muscle stimulator or learn to use TENS therapy during stroke rehabilitation.
Electrical stimulation has become a great tool in stroke rehabilitation. Two main types serve different therapeutic purposes. Learning about their mechanisms and applications helps stroke survivors and caregivers choose the best recovery options.
Neuromuscular Electrical Stimulation (NMES) creates muscle contractions through short electrical pulses delivered by surface electrodes to excite peripheral nerves [1]. This technology shows great promise for stroke survivors because their spinal motor neurons usually stay intact and responsive despite cortical damage [1].
NMES sends controlled electrical impulses that copy the signals our nervous system normally sends to muscles [2]. These impulses make targeted muscles contract and help strengthen weakened limbs to support motor recovery [2]. The stimulation settings include pulse frequencies of 10-100 Hz, amplitudes of 10-120 ms, and pulse widths from 200 μs to 1 ms [3].
Technical considerations: Stronger muscle contractions happen at higher frequencies but muscles get tired faster [3]. The pulse waveform can be monophasic, biphasic, or burst (polyphasic). Rehabilitation usually works better with monophasic or biphasic waveforms [4].
Functional Electrical Stimulation (FES) is a special type of NMES that combines stimulation with practical movements. These movements include lifting the foot while walking or making fingers grasp objects [2]. This method helps patients use their muscles again in daily activities [2].
Transcutaneous Electrical Nerve Stimulation (TENS) focuses on sensory nerves instead of muscles [5]. TENS blocks pain signals before they reach the brain. This technology started as a pain management tool [2].
TENS creates a tingling sensation where electrodes touch the skin rather than causing visible muscle movements [5]. The system works by stimulating nerve endings on the skin’s surface. This extra sensory input helps the brain reorganize motor control [6].
Stroke patients can easily use TENS devices at home [7]. Treatment sessions last between 20 to 60 minutes, and patients might need one to seven sessions each week [7].
TENS does more than just relieve pain. Research shows it can reduce spasticity in stroke patients’ lower limbs [7]. The results get even better when patients combine TENS with regular training exercises compared to exercise alone [3].
These technologies differ mainly in their targets and results [5]:
Research suggests using both types of stimulation together might work better than using just one [6]. This combined approach targets motor and sensory systems at the same time. The results are better than exercise alone, which only focuses on movement and muscle strength [6].
The right electrical stimulation approach at the right time can boost stroke recovery outcomes by a lot. Patient’s timing, impairment severity, and specific rehabilitation goals are vital factors that determine which method will work best.
NMES works best in the subacute stage of stroke recovery [1]. It targets muscles that stay weak or paralyzed but still have intact motor neurons [8]. This therapy helps strengthen muscles, reduces spasticity, and helps control movement when patients can’t move voluntarily [9].
Research shows promising results for patients with severe paresis. NMES helps improve functional motor abilities with significant positive effects (SMD, 0.41; 95% CI, 0.12-0.70; P=.005) [1]. Surface electrodes stimulate muscle contractions that mimic exercise therapy and improve strength and range of motion [10].
NMES applications for upper extremities have showed better outcomes for daily living activities (SMD, 0.34; 95% CI, 0.04-0.64; P=.02) [1]. Clinical trials reveal that early NMES use boosts motor function in affected limbs and improves daily activities. These benefits last at least six months after treatment ends [11].
TENS therapy helps manage pain and provides sensory stimulation. Scientists first developed it to relieve pain by modulating descending pain inhibitory systems [8]. Now it also helps improve functional performance and restore sensorimotor function in stroke survivors [8].
Gentle electrical signals block pain messages before reaching the brain [9]. TENS does more than control pain – it improves voluntary lower limb movement and strengthens dorsiflexors when combined with targeted training [8]. The therapy stimulates nerve endings on skin’s surface, which increases sensory input to the brain and helps reorganize motor control [10].
Studies show that TENS reduces spasticity and improves Composite Spasticity Scores in stroke patient’s plantar flexors [12]. High-frequency TENS (100 Hz) shows the best results for motor recovery [13].
Using NMES and TENS together gets better results than using either one alone. Research shows the TENS+NMES combination works better than single treatments to improve posture, boost independence, and reduce spasticity [6].
These therapies work together through different mechanisms. NMES activates muscles through motor neurons and targets muscle groups that passive exercise can’t reach, which speeds up strength gains [10]. TENS sends more sensory input to the brain and helps reorganize motor control pathways more effectively [10].
The combined approach maintains its benefits longer. Single therapies show good results at one month but lose effect by four months. However, using both therapies together keeps spasticity reduced through the fourth month of follow-up [6].
Patients should try moving their muscles during stimulation sessions to build stronger brain-muscle connections [9]. The treatment works even better when combined with regular therapies like specific exercises and strength training. This combination activates muscles better, reinforces correct movement patterns, and speeds up recovery [4].
Proper electrode placement serves as the life-blood of electrical stimulation therapy that helps stroke recovery. The most advanced TENS or NMES unit will not deliver optimal results without correct positioning and might cause patient discomfort.
Upper extremity stimulation requires electrode positioning around the shoulder, forearm, or hand based on which muscles need rehabilitation. Shoulder subluxation, a common post-stroke condition, needs one pair of electrodes over the supraspinatus and middle fibers of deltoids. A second pair should cover the anterior and posterior deltoid fibers to help relocate the humerus appropriately. Patients with significant anterior subluxation or internal rotation will benefit from electrodes placed on teres minor and posterior deltoid fibers for better posterior relocation.
Lower limb rehabilitation’s electrode placement varies by function:
The skin must be clean and dry before electrode application—alcohol prep pads work well. Patients should skip lotions as these affect conductivity. The electrode’s size should match the target muscle’s size. Small muscles need smaller electrodes for precision, while major muscle groups work better with larger ones.
The skin’s response needs regular checks. Temporary redness at the electrode site remains normal, but persistent irritation points to improper settings or placement that needs adjustment. Home device users should see their healthcare providers regularly to track progress and adjust their treatment plan as needed.
Absolute contraindications include:
Important placement restrictions: Electrodes must never go over the eyes, heart, reproductive organs, or exposed metal like pins or staples. The anterior neck region poses risks to the carotid sinus and should be avoided.
Metal implants need careful evaluation—modern titanium implants usually pose fewer risks than older metal types. Patients with impaired sensation or cognition require modified approaches with close monitoring and possibly lower intensity settings.
You need to match your specific rehabilitation needs with the right technology to find the ideal electrical stimulation device. The right device selection starts with understanding your recovery goals and talking to healthcare professionals about which options will best support your recovery.
A good TENS unit for stroke recovery should have multiple modes and customizable intensity settings to manage pain effectively. You should look for units with pre-set programs if pain relief is your main goal. These make daily use simple and consistent. Home-based therapy becomes easier with portable, rechargeable models that blend into your daily routines.
Your healthcare providers play a crucial role. They can suggest the right settings and usage protocols based on your condition. Stroke survivors need to talk about their medical history with therapists before buying any electrical stimulation device. Some conditions like pacemakers or specific heart problems might make TENS therapy unsuitable.
NMES devices with adjustable frequency and pulse width settings work best for muscle strengthening and motor recovery. You can stimulate two muscle groups at once with dual-channel models. This creates complex movement patterns you need for functional rehabilitation. Systems like the WalkAide and NESS L300 help with foot drop. They stimulate lower leg muscles during walking’s swing phase and improve leg clearance.
The NESS H200 is unique as the only FES device you can buy specifically for upper limb and hand rehabilitation. It uses five electrodes to stimulate different muscle groups. This helps with both key gripping and palmar grasping, which makes it valuable for patients who want to regain hand function.
Dual-function devices let you combine pain relief with muscle activation in one unit. The SaeboStim Pro shows this versatility well. Its pocket-sized, portable design delivers NMES for muscle activation, TENS for pain management, and sensory electrical stimulation options. The trigger button helps time muscle activation precisely during tasks like reaching or grasping.
A quality dual-function device should have these key features:
Your rehabilitation goals should guide your technology choice—TENS for pain relief, NMES for strengthening, or dual-function devices for complete recovery support.
The combination of electrical stimulation and other rehabilitation approaches creates better outcomes for stroke recovery. Research shows that using these therapies together works better than using them separately [14].
Physical therapy exercises work better with electrical stimulation. Studies show that TENS applied before targeted exercises boosts muscle activation and reduces spasticity [15]. This combination creates a mutually beneficial effect—NMES makes movements easier that patients cannot do on their own. As their strength improves, patients can gradually move to active exercise [6].
FES proves effective in rehabilitation, especially when you have conventional therapy. Clinical trials show that FES combined with rehabilitation creates better improvement in Barthel Index, Berg Balance Scale, and timed walking testscompared to rehabilitation alone [16]. FES stimulates targeted nerves to create specific functional movements and promotes neuroplasticity [17].
The best results need consistent application throughout recovery. Different studies suggest different treatment lengths, but most show that 30-60 minute sessions, with 20 sessions typically showing major functional improvements [6]. The right timing matters—early treatment (within days post-stroke) helps patients walk faster. Patients who receive FES start walking 2-3 days earlier than control groups [18].
Active participation is a vital part—patients should try voluntary movement during stimulation to build stronger neural pathways [14].
Stroke survivors can use electrical stimulation as a powerful tool on their road to recovery. TENS and NMES therapies each play unique but complementary roles. NMES helps strengthen weak muscles and improve motor control. TENS helps manage pain and provides important sensory feedback.
These two approaches work better together than separately. Research shows that using both treatments gives better long-term results than using just one, especially when you have to maintain the benefits over time.
The right electrode placement makes a huge difference in treatment success. Of course, you need to know the correct positions for upper and lower limbs to get the best stimulation safely. Patients should also know about any risks and take proper safety measures to avoid side effects.
You’ll need to match your device to your specific rehab needs. Therefore, someone looking mainly for pain relief might do better with a TENS unit. People focused on rebuilding muscle strength might choose an NMES device instead. Dual-function systems can support a complete recovery by offering both options.
These treatments work best when combined smoothly with traditional rehab methods. Using electrical stimulation alongside physical therapy creates great opportunities for brain plasticity and functional improvements. Regular use throughout recovery will give the best possible results.
Stroke survivors and their caregivers can use these electrical stimulation options as a great way to get help during recovery. The experience after stroke brings major challenges, but these technologies offer proven ways to rebuild strength, control pain, and restore function. This helps people work toward greater independence and a better quality of life.
Understanding the differences between TENS and NMES can help stroke survivors choose the most effective electrical stimulation therapy for their specific recovery needs.
• NMES targets motor nerves to strengthen muscles and improve movement, while TENS focuses on sensory nerves for pain relief and spasticity reduction
• Combining both NMES and TENS therapies produces superior long-term results compared to using either treatment alone
• Proper electrode placement is crucial for safety and effectiveness – avoid areas near the heart, eyes, or metal implants
• Early intervention within days post-stroke yields faster recovery, with 30-60 minute sessions showing significant functional improvements
• Integration with physical therapy maximizes results – patients should actively attempt movement during stimulation to strengthen neural pathways
The key to successful stroke recovery lies in selecting the right combination of electrical stimulation therapies and integrating them consistently with conventional rehabilitation approaches for optimal neuroplasticity and functional restoration.
[1] – https://www.sciencedirect.com/science/article/pii/S2590109521000811
[2] – https://www.flintrehab.com/electrical-stimulation-for-stroke-patients/?srsltid=AfmBOor-_pDSzjsRqoVCNTeRAvVBO3g0rUonuB8QJ3HezuC0J1LSHZVC
[3] – https://www.saebo.com/blogs/advice/electrical-stimulation-for-stroke-rehab-how-nmes-ses-and-tens-boost-recovery?srsltid=AfmBOoq6Pd5LGvFhyytPTaT0DGYPlC-bHVTSOzPKmILhAcCwUV6fMOH4
[4] – https://www.saebo.com/blogs/advice/electrical-stimulation-for-stroke-rehab-how-nmes-ses-and-tens-boost-recovery?srsltid=AfmBOoolKvkTI53iijGYdc9RVJ2toyBGMrB0W4JdZr50D3oze115fUg3
[5] – https://www.flintrehab.com/nmes-vs-tens/?srsltid=AfmBOoogpVUuy32nxMCmZIu5r-6M7oMOKcJPYodlt7VBN2i0-mSB2Cz8
[6] – https://pmc.ncbi.nlm.nih.gov/articles/PMC12020091/
[7] – https://evidence.nihr.ac.uk/alert/transcutaneous-electrical-stimulation-tens-may-help-lower-limb-spasticity-after-stroke/
[8] – https://pmc.ncbi.nlm.nih.gov/articles/PMC7005350/
[9] – https://www.saebo.com/blogs/advice/electrical-stimulation-for-stroke-rehab-how-nmes-ses-and-tens-boost-recovery?srsltid=AfmBOor7bVgmn8vWkyCv6d97TzWK5uLkk8YQyDqIbMIa-XjBU1-UKux6
[10] – https://bmcsportsscimedrehabil.biomedcentral.com/articles/10.1186/s13102-025-01155-w
[11] – https://www.medicaljournals.se/jrm/content/html/10.2340/16501977-0807
[12] – https://pmc.ncbi.nlm.nih.gov/articles/PMC8410308/
[13] – https://www.tandfonline.com/doi/full/10.1080/09638288.2025.2453640
[14] – https://www.saebo.com/blogs/advice/electrical-stimulation-for-stroke-rehab-how-nmes-ses-and-tens-boost-recovery?srsltid=AfmBOoqT_55C4GGcfNZ2sAw7ApZZCp8iiqQ3-Gwt5f9VAUfR025zxZdX
[15] – https://www.ahajournals.org/doi/10.1161/strokeaha.107.490318
[16] – https://pmc.ncbi.nlm.nih.gov/articles/PMC8984173/
[17] – https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1272992/full
[18] – https://www.ahajournals.org/doi/10.1161/01.str.0000149623.24906.63
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